G883-0796 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

G883-0796 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
G883-0796 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0796
N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0796

Molecular Formula

C28H25FN4O3 (C28 H25 FN4 O3)

Compound Name

N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

IUPAC name

N-{[1-(4-fluorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-3-[3-(4-methylphenyl)-124-oxadiazol-5-yl]propanamide

SMILES

Cc(cc1)ccc1-c1noc(CCC(NCc(cc2)cc(CC3)c2N3C(c(cc2)ccc2F)=O)=O)n1

InChI

InChI=1S/C28H25FN4O3/c1-18-2-5-20(6-3-18)27-31-26(36-32-27)13-12-25(34)30-17-19-4-11-24-22(16-19)14-15-33(24)28(35)21-7-9-23(29)10-8-21/h2-11,16H,12-15,17H2,1H3,(H,30,34)

InChI Key

PWJPPPCKLKBWIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165563

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.848

Distribution Coefficient, logD

4.848

Water Solubility, LogSw

-4.56

Polar Surface Area

71.460

Acid Dissociation Constant (pKa)

13.87

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

G883-0796 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

MCL1 Targeted Library (12200 compounds)

Nucleic Acid Ligands (8311 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0796 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0796?
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What is the minimum amount of G883-0796 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0796
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0796
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0796 available by request