G883-0848 Screening compound: 3-acetamido-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

G883-0848 Screening compound: 3-acetamido-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide
G883-0848 Screening compound: 3-acetamido-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0848
3-acetamido-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0848

Molecular Formula

C25H22FN3O3 (C25 H22 FN3 O3)

Compound Name

3-acetamido-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

IUPAC name

3-acetamido-N-{[1-(4-fluorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}benzamide

SMILES

CC(Nc1cccc(C(NCc(cc2)cc(CC3)c2N3C(c(cc2)ccc2F)=O)=O)c1)=O

InChI

InChI=1S/C25H22FN3O3/c1-16(30)28-22-4-2-3-20(14-22)24(31)27-15-17-5-10-23-19(13-17)11-12-29(23)25(32)18-6-8-21(26)9-7-18/h2-10,13-14H,11-12,15H2,1H3,(H,27,31)(H,28,30)

InChI Key

ATYFUUKDZIFFBA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165585

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.210

Distribution Coefficient, logD

3.210

Water Solubility, LogSw

-3.44

Polar Surface Area

63.592

Acid Dissociation Constant (pKa)

12.52

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

G883-0848 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0848?
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What is the minimum amount of G883-0848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0848 available by request