G883-0853 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(4-fluorophenoxy)acetamide

G883-0853 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(4-fluorophenoxy)acetamide
G883-0853 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(4-fluorophenoxy)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0853
N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(4-fluorophenoxy)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0853

Molecular Formula

C24H20F2N2O3 (C24 H20 F2 N2 O3)

Compound Name

N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(4-fluorophenoxy)acetamide

IUPAC name

N-{[1-(4-fluorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-2-(4-fluorophenoxy)acetamide

SMILES

O=C(COc(cc1)ccc1F)NCc(cc1)cc(CC2)c1N2C(c(cc1)ccc1F)=O

InChI

InChI=1S/C24H20F2N2O3/c25-19-4-2-17(3-5-19)24(30)28-12-11-18-13-16(1-10-22(18)28)14-27-23(29)15-31-21-8-6-20(26)7-9-21/h1-10,13H,11-12,14-15H2,(H,27,29)

InChI Key

CWTUHFJXOLNSAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165589

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.628

Distribution Coefficient, logD

3.628

Water Solubility, LogSw

-3.95

Polar Surface Area

47.616

Acid Dissociation Constant (pKa)

14.02

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

G883-0853 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

Nucleic Acid Ligands (8311 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0853 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0853?
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What is the minimum amount of G883-0853 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0853
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0853
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0853 available by request