G883-0859 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-methyl-1H-pyrazole-5-carboxamide

G883-0859 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-methyl-1H-pyrazole-5-carboxamide
G883-0859 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-methyl-1H-pyrazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0859
N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-methyl-1H-pyrazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0859

Molecular Formula

C21H19FN4O2 (C21 H19 FN4 O2)

Compound Name

N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-methyl-1H-pyrazole-5-carboxamide

IUPAC name

N-{[1-(4-fluorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-1-methyl-1H-pyrazole-5-carboxamide

SMILES

Cn1nccc1C(NCc(cc1)cc(CC2)c1N2C(c(cc1)ccc1F)=O)=O

InChI

InChI=1S/C21H19FN4O2/c1-25-19(8-10-24-25)20(27)23-13-14-2-7-18-16(12-14)9-11-26(18)21(28)15-3-5-17(22)6-4-15/h2-8,10,12H,9,11,13H2,1H3,(H,23,27)

InChI Key

USHQXVKRJFBGSK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165590

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.157

Distribution Coefficient, logD

2.157

Water Solubility, LogSw

-2.82

Polar Surface Area

53.981

Acid Dissociation Constant (pKa)

12.50

Base Dissociation Constant (pKb)

1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

G883-0859 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

3D-Diversity Natural-Product-Like Library (18102 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS targets activity set (6557 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0859 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0859?
Check Price and Availability of G883-0859, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0859 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0859
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0859
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0859 available by request