G883-1042 Screening compound: 5-bromo-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}furan-2-carboxamide

G883-1042 Screening compound: 5-bromo-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}furan-2-carboxamide
G883-1042 Screening compound: 5-bromo-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1042
5-bromo-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1042

Molecular Formula

C20H16BrN3O3 (C20 H16 BrN3 O3)

Compound Name

5-bromo-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}furan-2-carboxamide

IUPAC name

5-bromo-N-{[1-(pyridine-4-carbonyl)-23-dihydro-1H-indol-5-yl]methyl}furan-2-carboxamide

SMILES

O=C(c(o1)ccc1Br)NCc(cc1)cc(CC2)c1N2C(c1ccncc1)=O

InChI

InChI=1S/C20H16BrN3O3/c21-18-4-3-17(27-18)19(25)23-12-13-1-2-16-15(11-13)7-10-24(16)20(26)14-5-8-22-9-6-14/h1-6,8-9,11H,7,10,12H2,(H,23,25)

InChI Key

AVJGYJGWDONJFV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165597

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.27

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.451

Distribution Coefficient, logD

2.451

Water Solubility, LogSw

-2.47

Polar Surface Area

58.685

Acid Dissociation Constant (pKa)

11.18

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

G883-1042 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1042 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1042?
Check Price and Availability of G883-1042, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1042 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1042
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1042
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1042 available by request