G883-1045 Screening compound: N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}cyclobutanecarboxamide

G883-1045 Screening compound: N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}cyclobutanecarboxamide
G883-1045 Screening compound: N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1045
N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1045

Molecular Formula

C20H21N3O2 (C20 H21 N3 O2)

Compound Name

N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}cyclobutanecarboxamide

IUPAC name

N-{[1-(pyridine-4-carbonyl)-23-dihydro-1H-indol-5-yl]methyl}cyclobutanecarboxamide

SMILES

O=C(C1CCC1)NCc(cc1)cc(CC2)c1N2C(c1ccncc1)=O

InChI

InChI=1S/C20H21N3O2/c24-19(15-2-1-3-15)22-13-14-4-5-18-17(12-14)8-11-23(18)20(25)16-6-9-21-10-7-16/h4-7,9-10,12,15H,1-3,8,11,13H2,(H,22,24)

InChI Key

ALZXSETVARINAZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

335.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.085

Distribution Coefficient, logD

1.085

Water Solubility, LogSw

-1.51

Polar Surface Area

50.282

Acid Dissociation Constant (pKa)

13.63

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G883-1045 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • GPCR
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G883-1045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1045?
Check Price and Availability of G883-1045, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1045 available by request