G883-1072 Screening compound: 2-ethyl-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}butanamide

G883-1072 Screening compound: 2-ethyl-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}butanamide
G883-1072 Screening compound: 2-ethyl-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1072
2-ethyl-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1072

Molecular Formula

C21H25N3O2 (C21 H25 N3 O2)

Compound Name

2-ethyl-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}butanamide

IUPAC name

2-ethyl-N-{[1-(pyridine-4-carbonyl)-23-dihydro-1H-indol-5-yl]methyl}butanamide

SMILES

CCC(CC)C(NCc(cc1)cc(CC2)c1N2C(c1ccncc1)=O)=O

InChI

InChI=1S/C21H25N3O2/c1-3-16(4-2)20(25)23-14-15-5-6-19-18(13-15)9-12-24(19)21(26)17-7-10-22-11-8-17/h5-8,10-11,13,16H,3-4,9,12,14H2,1-2H3,(H,23,25)

InChI Key

KGFKPQZUVPBUJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165608

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.441

Distribution Coefficient, logD

2.441

Water Solubility, LogSw

-2.45

Polar Surface Area

50.030

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G883-1072 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1072 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1072?
Check Price and Availability of G883-1072, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1072 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1072
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1072
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1072 available by request