G883-1503 Screening compound: 3-(4-methoxyphenyl)-N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}propanamide

G883-1503 Screening compound: 3-(4-methoxyphenyl)-N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}propanamide
G883-1503 Screening compound: 3-(4-methoxyphenyl)-N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1503
3-(4-methoxyphenyl)-N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1503

Molecular Formula

C27H28N2O3 (C27 H28 N2 O3)

Compound Name

3-(4-methoxyphenyl)-N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}propanamide

IUPAC name

3-(4-methoxyphenyl)-N-{[1-(3-methylbenzoyl)-23-dihydro-1H-indol-5-yl]methyl}propanamide

SMILES

Cc1cccc(C(N(CC2)c3c2cc(CNC(CCc(cc2)ccc2OC)=O)cc3)=O)c1

InChI

InChI=1S/C27H28N2O3/c1-19-4-3-5-23(16-19)27(31)29-15-14-22-17-21(8-12-25(22)29)18-28-26(30)13-9-20-6-10-24(32-2)11-7-20/h3-8,10-12,16-17H,9,13-15,18H2,1-2H3,(H,28,30)

InChI Key

KOUSLFXYPGQVKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165635

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.358

Distribution Coefficient, logD

4.358

Water Solubility, LogSw

-4.31

Polar Surface Area

47.661

Acid Dissociation Constant (pKa)

13.47

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

G883-1503 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1503 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1503?
Check Price and Availability of G883-1503, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1503 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1503
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1503
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1503 available by request