G883-1507 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide

G883-1507 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide
G883-1507 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1507
N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1507

Molecular Formula

C25H22N2O4 (C25 H22 N2 O4)

Compound Name

N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide

IUPAC name

N-{[1-(3-methylbenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-2H-13-benzodioxole-5-carboxamide

SMILES

Cc1cccc(C(N(CC2)c3c2cc(CNC(c(cc2)cc4c2OCO4)=O)cc3)=O)c1

InChI

InChI=1S/C25H22N2O4/c1-16-3-2-4-20(11-16)25(29)27-10-9-18-12-17(5-7-21(18)27)14-26-24(28)19-6-8-22-23(13-19)31-15-30-22/h2-8,11-13H,9-10,14-15H2,1H3,(H,26,28)

InChI Key

ZOFSEQNGNDFHLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165638

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.888

Distribution Coefficient, logD

3.888

Water Solubility, LogSw

-3.95

Polar Surface Area

57.446

Acid Dissociation Constant (pKa)

13.48

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G883-1507 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1507 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1507?
Check Price and Availability of G883-1507, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1507 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1507
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1507
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1507 available by request