G883-1542 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(morpholine-4-sulfonyl)piperidine-4-carboxamide

G883-1542 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(morpholine-4-sulfonyl)piperidine-4-carboxamide
G883-1542 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(morpholine-4-sulfonyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1542
N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(morpholine-4-sulfonyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1542

Molecular Formula

C27H34N4O5S (C27 H34 N4 O5 S)

Compound Name

N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(morpholine-4-sulfonyl)piperidine-4-carboxamide

IUPAC name

N-{[1-(3-methylbenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-1-(morpholine-4-sulfonyl)piperidine-4-carboxamide

SMILES

Cc1cccc(C(N(CC2)c3c2cc(CNC(C(CC2)CCN2S(N2CCOCC2)(=O)=O)=O)cc3)=O)c1

InChI

InChI=1S/C27H34N4O5S/c1-20-3-2-4-24(17-20)27(33)31-12-9-23-18-21(5-6-25(23)31)19-28-26(32)22-7-10-29(11-8-22)37(34,35)30-13-15-36-16-14-30/h2-6,17-18,22H,7-16,19H2,1H3,(H,28,32)

InChI Key

WSOSKVJXRHLDGO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165665

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

526.66

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.725

Distribution Coefficient, logD

1.725

Water Solubility, LogSw

-2.47

Polar Surface Area

82.356

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.10

G883-1542 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1542 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1542?
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What is the minimum amount of G883-1542 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1542
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1542
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1542 available by request