G883-1547 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

G883-1547 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide
G883-1547 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1547
N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1547

Molecular Formula

C27H34N4O4S (C27 H34 N4 O4 S)

Compound Name

N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

IUPAC name

N-{[1-(3-methylbenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

SMILES

Cc1cccc(C(N(CC2)c3c2cc(CNC(C(CC2)CCN2S(N2CCCC2)(=O)=O)=O)cc3)=O)c1

InChI

InChI=1S/C27H34N4O4S/c1-20-5-4-6-24(17-20)27(33)31-16-11-23-18-21(7-8-25(23)31)19-28-26(32)22-9-14-30(15-10-22)36(34,35)29-12-2-3-13-29/h4-8,17-18,22H,2-3,9-16,19H2,1H3,(H,28,32)

InChI Key

FUMRABLOHGHWAH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165670

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

510.66

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.402

Distribution Coefficient, logD

2.402

Water Solubility, LogSw

-2.72

Polar Surface Area

74.813

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.10

G883-1547 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1547 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1547?
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What is the minimum amount of G883-1547 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1547
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1547
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1547 available by request