G884-1251 Screening compound: N-[(4-ethylphenyl)methyl]-2-{4-[(4-methylphenyl)methyl]-2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}acetamide

G884-1251 Screening compound: N-[(4-ethylphenyl)methyl]-2-{4-[(4-methylphenyl)methyl]-2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}acetamide
G884-1251 Screening compound: N-[(4-ethylphenyl)methyl]-2-{4-[(4-methylphenyl)methyl]-2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G884-1251
N-[(4-ethylphenyl)methyl]-2-{4-[(4-methylphenyl)methyl]-2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G884-1251

Molecular Formula

C26H26N4O3 (C26 H26 N4 O3)

Compound Name

N-[(4-ethylphenyl)methyl]-2-{4-[(4-methylphenyl)methyl]-2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}acetamide

IUPAC name

N-[(4-ethylphenyl)methyl]-2-{4-[(4-methylphenyl)methyl]-23-dioxo-1H2H3H4H-pyrido[23-b]pyrazin-1-yl}acetamide

SMILES

CCc1ccc(CNC(CN(c2cccnc2N(Cc2ccc(C)cc2)C2=O)C2=O)=O)cc1

InChI

InChI=1S/C26H26N4O3/c1-3-19-10-12-20(13-11-19)15-28-23(31)17-29-22-5-4-14-27-24(22)30(26(33)25(29)32)16-21-8-6-18(2)7-9-21/h4-14H,3,15-17H2,1-2H3,(H,28,31)

InChI Key

SOQTTXQKOQEVQF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27166018

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.869

Distribution Coefficient, logD

3.869

Water Solubility, LogSw

-3.78

Polar Surface Area

65.326

Acid Dissociation Constant (pKa)

13.24

Base Dissociation Constant (pKb)

0.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G884-1251 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G884-1251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G884-1251?
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What is the minimum amount of G884-1251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G884-1251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G884-1251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G884-1251 available by request