G887-0166 Screening compound: 6-ethyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}thieno[2,3-d]pyrimidin-4-amine

G887-0166 Screening compound: 6-ethyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}thieno[2,3-d]pyrimidin-4-amine
G887-0166 Screening compound: 6-ethyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}thieno[2,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G887-0166
6-ethyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}thieno[2,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G887-0166

Molecular Formula

C21H26FN5S (C21 H26 FN5 S)

Compound Name

6-ethyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}thieno[2,3-d]pyrimidin-4-amine

IUPAC name

6-ethyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}thieno[23-d]pyrimidin-4-amine

SMILES

CCc1cc2c(NCCCN(CC3)CCN3c(cc3)ccc3F)ncnc2s1

InChI

InChI=1S/C21H26FN5S/c1-2-18-14-19-20(24-15-25-21(19)28-18)23-8-3-9-26-10-12-27(13-11-26)17-6-4-16(22)5-7-17/h4-7,14-15H,2-3,8-13H2,1H3,(H,23,24,25)

InChI Key

MCRQXRCCTOIOJG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15072796

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.54

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.375

Distribution Coefficient, logD

4.114

Water Solubility, LogSw

-4.05

Polar Surface Area

39.112

Acid Dissociation Constant (pKa)

18.27

Base Dissociation Constant (pKb)

7.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

G887-0166 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G887-0166 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G887-0166?
Check Price and Availability of G887-0166, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G887-0166 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G887-0166
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G887-0166
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G887-0166 available by request