G893-0271 Screening compound: 2-(4-acetamidophenyl)-3-oxo-N-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-isoindole-1-carboxamide

G893-0271 Screening compound: 2-(4-acetamidophenyl)-3-oxo-N-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-isoindole-1-carboxamide
G893-0271 Screening compound: 2-(4-acetamidophenyl)-3-oxo-N-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-isoindole-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G893-0271
2-(4-acetamidophenyl)-3-oxo-N-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-isoindole-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G893-0271

Molecular Formula

C23H27N3O4 (C23 H27 N3 O4)

Compound Name

2-(4-acetamidophenyl)-3-oxo-N-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-isoindole-1-carboxamide

IUPAC name

2-(4-acetamidophenyl)-3-oxo-N-[3-(propan-2-yloxy)propyl]-23-dihydro-1H-isoindole-1-carboxamide

SMILES

CC(C)OCCCNC(C(c(cccc1)c1C1=O)N1c(cc1)ccc1NC(C)=O)=O

InChI

InChI=1S/C23H27N3O4/c1-15(2)30-14-6-13-24-22(28)21-19-7-4-5-8-20(19)23(29)26(21)18-11-9-17(10-12-18)25-16(3)27/h4-5,7-12,15,21H,6,13-14H2,1-3H3,(H,24,28)(H,25,27)/t21-/m0/s1

InChI Key

PRWIQOVWRMHGQP-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27167128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.773

Distribution Coefficient, logD

1.773

Water Solubility, LogSw

-2.55

Polar Surface Area

70.667

Acid Dissociation Constant (pKa)

12.76

Base Dissociation Constant (pKb)

0.69

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.78

G893-0271 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G893-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G893-0271?
Check Price and Availability of G893-0271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G893-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G893-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G893-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G893-0271 available by request