G893-0454 Screening compound: 2-(2-methoxybenzyl)-N~1~-(2-methoxyethyl)-3-oxo-1-isoindolinecarboxamide

G893-0454 Screening compound: 2-(2-methoxybenzyl)-N~1~-(2-methoxyethyl)-3-oxo-1-isoindolinecarboxamide
G893-0454 Screening compound: 2-(2-methoxybenzyl)-N~1~-(2-methoxyethyl)-3-oxo-1-isoindolinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G893-0454
2-(2-methoxybenzyl)-N~1~-(2-methoxyethyl)-3-oxo-1-isoindolinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G893-0454

Molecular Formula

C20H22N2O4 (C20 H22 N2 O4)

Compound Name

2-(2-methoxybenzyl)-N~1~-(2-methoxyethyl)-3-oxo-1-isoindolinecarboxamide

IUPAC name

N-(2-methoxyethyl)-2-[(2-methoxyphenyl)methyl]-3-oxo-23-dihydro-1H-isoindole-1-carboxamide

SMILES

COCCNC(C(c1c2cccc1)N(Cc(cccc1)c1OC)C2=O)=O

InChI

InChI=1S/C20H22N2O4/c1-25-12-11-21-19(23)18-15-8-4-5-9-16(15)20(24)22(18)13-14-7-3-6-10-17(14)26-2/h3-10,18H,11-13H2,1-2H3,(H,21,23)/t18-/m0/s1

InChI Key

SLPFTAWKKSFWNL-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15073779

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.227

Distribution Coefficient, logD

2.227

Water Solubility, LogSw

-2.89

Polar Surface Area

56.788

Acid Dissociation Constant (pKa)

13.91

Base Dissociation Constant (pKb)

-0.67

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.00

G893-0454 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G893-0454 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G893-0454?
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What is the minimum amount of G893-0454 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G893-0454
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G893-0454
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G893-0454 available by request