G895-1027 Screening compound: N-(4-ethylphenyl)-2,5-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

G895-1027 Screening compound: N-(4-ethylphenyl)-2,5-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide
G895-1027 Screening compound: N-(4-ethylphenyl)-2,5-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G895-1027
N-(4-ethylphenyl)-2,5-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G895-1027

Molecular Formula

C22H26N4OS (C22 H26 N4 OS)

Compound Name

N-(4-ethylphenyl)-2,5-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(4-ethylphenyl)-25-dimethyl-4-(piperidin-1-yl)thieno[23-d]pyrimidine-6-carboxamide

SMILES

CCc(cc1)ccc1NC(c1c(C)c2c(N3CCCCC3)nc(C)nc2s1)=O

InChI

InChI=1S/C22H26N4OS/c1-4-16-8-10-17(11-9-16)25-21(27)19-14(2)18-20(26-12-6-5-7-13-26)23-15(3)24-22(18)28-19/h8-11H,4-7,12-13H2,1-3H3,(H,25,27)

InChI Key

VLUIEYDGDASIDZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074137

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.754

Distribution Coefficient, logD

5.726

Water Solubility, LogSw

-5.53

Polar Surface Area

46.004

Acid Dissociation Constant (pKa)

10.55

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

G895-1027 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G895-1027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G895-1027?
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What is the minimum amount of G895-1027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G895-1027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G895-1027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G895-1027 available by request