G898-0145 Screening compound: N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]-4-(morpholin-4-yl)-4-oxobutanamide

G898-0145 Screening compound: N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]-4-(morpholin-4-yl)-4-oxobutanamide
G898-0145 Screening compound: N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]-4-(morpholin-4-yl)-4-oxobutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G898-0145
N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]-4-(morpholin-4-yl)-4-oxobutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G898-0145

Molecular Formula

C22H28N4O4 (C22 H28 N4 O4)

Compound Name

N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]-4-(morpholin-4-yl)-4-oxobutanamide

IUPAC name

N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]-4-(morpholin-4-yl)-4-oxobutanamide

SMILES

Cc1c(cc(cc2)NC(CCC(N3CCOCC3)=O)=O)c2nc(N2CCOCC2)c1

InChI

InChI=1S/C22H28N4O4/c1-16-14-20(25-6-10-29-11-7-25)24-19-3-2-17(15-18(16)19)23-21(27)4-5-22(28)26-8-12-30-13-9-26/h2-3,14-15H,4-13H2,1H3,(H,23,27)

InChI Key

PRYSXLLUEYIVLD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074354

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.763

Distribution Coefficient, logD

1.762

Water Solubility, LogSw

-2.41

Polar Surface Area

66.572

Acid Dissociation Constant (pKa)

11.10

Base Dissociation Constant (pKb)

4.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G898-0145 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G898-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G898-0145?
Check Price and Availability of G898-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G898-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G898-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G898-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G898-0145 available by request