G898-0265 Screening compound: 3-chloro-4-fluoro-N-[4-methyl-2-(piperidin-1-yl)quinolin-6-yl]benzamide

G898-0265 Screening compound: 3-chloro-4-fluoro-N-[4-methyl-2-(piperidin-1-yl)quinolin-6-yl]benzamide
G898-0265 Screening compound: 3-chloro-4-fluoro-N-[4-methyl-2-(piperidin-1-yl)quinolin-6-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G898-0265
3-chloro-4-fluoro-N-[4-methyl-2-(piperidin-1-yl)quinolin-6-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G898-0265

Molecular Formula

C22H21ClFN3O (C22 H21 ClFN3 O)

Compound Name

3-chloro-4-fluoro-N-[4-methyl-2-(piperidin-1-yl)quinolin-6-yl]benzamide

IUPAC name

3-chloro-4-fluoro-N-[4-methyl-2-(piperidin-1-yl)quinolin-6-yl]benzamide

SMILES

Cc1c(cc(cc2)NC(c(cc3)cc(Cl)c3F)=O)c2nc(N2CCCCC2)c1

InChI

InChI=1S/C22H21ClFN3O/c1-14-11-21(27-9-3-2-4-10-27)26-20-8-6-16(13-17(14)20)25-22(28)15-5-7-19(24)18(23)12-15/h5-8,11-13H,2-4,9-10H2,1H3,(H,25,28)

InChI Key

YOURRDRQDRLPQX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074379

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.88

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.029

Distribution Coefficient, logD

5.935

Water Solubility, LogSw

-6.16

Polar Surface Area

34.576

Acid Dissociation Constant (pKa)

8.02

Base Dissociation Constant (pKb)

4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G898-0265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Lipid Metabolism Library (9174 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G898-0265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G898-0265?
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What is the minimum amount of G898-0265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G898-0265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G898-0265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G898-0265 available by request