G898-0521 Screening compound: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-2-(furan-2-yl)quinoline-4-carboxamide

G898-0521 Screening compound: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-2-(furan-2-yl)quinoline-4-carboxamide
G898-0521 Screening compound: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-2-(furan-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G898-0521
N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-2-(furan-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G898-0521

Molecular Formula

C30H29N5O2 (C30 H29 N5 O2)

Compound Name

N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-2-(furan-2-yl)quinoline-4-carboxamide

IUPAC name

N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-2-(furan-2-yl)quinoline-4-carboxamide

SMILES

CCN(CC1)CCN1c1cc(C)c(cc(cc2)NC(c3cc(-c4ccco4)nc4ccccc34)=O)c2n1

InChI

InChI=1S/C30H29N5O2/c1-3-34-12-14-35(15-13-34)29-17-20(2)23-18-21(10-11-26(23)33-29)31-30(36)24-19-27(28-9-6-16-37-28)32-25-8-5-4-7-22(24)25/h4-11,16-19H,3,12-15H2,1-2H3,(H,31,36)

InChI Key

MQFQTBXEUJNRNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074432

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.093

Distribution Coefficient, logD

5.405

Water Solubility, LogSw

-5.62

Polar Surface Area

54.751

Acid Dissociation Constant (pKa)

11.53

Base Dissociation Constant (pKb)

7.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.30

G898-0521 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G898-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G898-0521?
Check Price and Availability of G898-0521, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G898-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G898-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G898-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G898-0521 available by request