G900-0052 Screening compound: 2-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinolin-8-ol

G900-0052 Screening compound: 2-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinolin-8-ol
G900-0052 Screening compound: 2-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound G900-0052
2-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G900-0052

Molecular Formula

C21H18F3N3O2 (C21 H18 F3 N3 O2)

Compound Name

2-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinolin-8-ol

IUPAC name

2-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinolin-8-ol

SMILES

Oc(cccc1cc2)c1nc2C(N(CC1)CCN1c1cccc(C(F)(F)F)c1)=O

InChI

InChI=1S/C21H18F3N3O2/c22-21(23,24)15-4-2-5-16(13-15)26-9-11-27(12-10-26)20(29)17-8-7-14-3-1-6-18(28)19(14)25-17/h1-8,13,28H,9-12H2

InChI Key

FWBMRGSDJVTQLS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074498

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.39

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.011

Distribution Coefficient, logD

3.995

Water Solubility, LogSw

-3.92

Polar Surface Area

45.796

Acid Dissociation Constant (pKa)

8.83

Base Dissociation Constant (pKb)

1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G900-0052 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Autophagy-Targeted Library (4564 compounds)

Hsp90-Targeted Library (11355 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G900-0052 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G900-0052?
Check Price and Availability of G900-0052, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G900-0052 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G900-0052
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G900-0052
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G900-0052 available by request