G900-0116 Screening compound: 8-hydroxy-N-(3,4,5-trimethoxyphenyl)quinoline-2-carboxamide

G900-0116 Screening compound: 8-hydroxy-N-(3,4,5-trimethoxyphenyl)quinoline-2-carboxamide
G900-0116 Screening compound: 8-hydroxy-N-(3,4,5-trimethoxyphenyl)quinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G900-0116
8-hydroxy-N-(3,4,5-trimethoxyphenyl)quinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G900-0116

Molecular Formula

C19H18N2O5 (C19 H18 N2 O5)

Compound Name

8-hydroxy-N-(3,4,5-trimethoxyphenyl)quinoline-2-carboxamide

IUPAC name

8-hydroxy-N-(345-trimethoxyphenyl)quinoline-2-carboxamide

SMILES

COc1cc(NC(c(ccc2ccc3)nc2c3O)=O)cc(OC)c1OC

InChI

InChI=1S/C19H18N2O5/c1-24-15-9-12(10-16(25-2)18(15)26-3)20-19(23)13-8-7-11-5-4-6-14(22)17(11)21-13/h4-10,22H,1-3H3,(H,20,23)

InChI Key

AMWWKZUMWGRURP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074508

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.36

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.696

Distribution Coefficient, logD

2.680

Water Solubility, LogSw

-3.38

Polar Surface Area

71.957

Acid Dissociation Constant (pKa)

8.83

Base Dissociation Constant (pKb)

1.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

G900-0116 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

C-Met Library (15277 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with G900-0116 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G900-0116?
Check Price and Availability of G900-0116, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G900-0116 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G900-0116
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G900-0116
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G900-0116 available by request