G923-0223 Screening compound: 6-(4-methylphenyl)-N-[(4-methylphenyl)methyl]-3-(3-nitrophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

G923-0223 Screening compound: 6-(4-methylphenyl)-N-[(4-methylphenyl)methyl]-3-(3-nitrophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide
G923-0223 Screening compound: 6-(4-methylphenyl)-N-[(4-methylphenyl)methyl]-3-(3-nitrophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G923-0223
6-(4-methylphenyl)-N-[(4-methylphenyl)methyl]-3-(3-nitrophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G923-0223

Molecular Formula

C28H23N5O3 (C28 H23 N5 O3)

Compound Name

6-(4-methylphenyl)-N-[(4-methylphenyl)methyl]-3-(3-nitrophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

IUPAC name

6-(4-methylphenyl)-N-[(4-methylphenyl)methyl]-3-(3-nitrophenyl)-2H-pyrazolo[34-b]pyridine-4-carboxamide

SMILES

Cc1ccc(CNC(c2cc(-c3ccc(C)cc3)nc3n[nH]c(-c4cccc([N+]([O-])=O)c4)c23)=O)cc1

InChI

InChI=1S/C28H23N5O3/c1-17-6-10-19(11-7-17)16-29-28(34)23-15-24(20-12-8-18(2)9-13-20)30-27-25(23)26(31-32-27)21-4-3-5-22(14-21)33(35)36/h3-15H,16H2,1-2H3,(H,29,34)(H,30,31,32)

InChI Key

KMDBDEODYUFDGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15075322

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.805

Distribution Coefficient, logD

6.799

Water Solubility, LogSw

-5.91

Polar Surface Area

90.679

Acid Dissociation Constant (pKa)

4.10

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.70

G923-0223 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G923-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G923-0223?
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What is the minimum amount of G923-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G923-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G923-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G923-0223 available by request