G923-0248 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-(4-ethoxyphenyl)-3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

G923-0248 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-(4-ethoxyphenyl)-3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide
G923-0248 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-(4-ethoxyphenyl)-3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G923-0248
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-(4-ethoxyphenyl)-3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G923-0248

Molecular Formula

C31H29FN4O4 (C31 H29 FN4 O4)

Compound Name

N-[2-(3,4-dimethoxyphenyl)ethyl]-6-(4-ethoxyphenyl)-3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

IUPAC name

N-[2-(34-dimethoxyphenyl)ethyl]-6-(4-ethoxyphenyl)-3-(4-fluorophenyl)-2H-pyrazolo[34-b]pyridine-4-carboxamide

SMILES

CCOc(cc1)ccc1-c1nc2n[nH]c(-c(cc3)ccc3F)c2c(C(NCCc(cc2)cc(OC)c2OC)=O)c1

InChI

InChI=1S/C31H29FN4O4/c1-4-40-23-12-8-20(9-13-23)25-18-24(28-29(35-36-30(28)34-25)21-6-10-22(32)11-7-21)31(37)33-16-15-19-5-14-26(38-2)27(17-19)39-3/h5-14,17-18H,4,15-16H2,1-3H3,(H,33,37)(H,34,35,36)

InChI Key

ASSBSRFTMZGUMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15075333

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

540.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.887

Distribution Coefficient, logD

5.886

Water Solubility, LogSw

-5.80

Polar Surface Area

79.523

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

1.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.40

G923-0248 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

ACE2 Library (3043 compounds)

Antiviral Annotated Library (21441 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G923-0248 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G923-0248?
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What is the minimum amount of G923-0248 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G923-0248
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G923-0248
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G923-0248 available by request