G923-0451 Screening compound: N-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-6-(4-methylphenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

G923-0451 Screening compound: N-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-6-(4-methylphenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide
G923-0451 Screening compound: N-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-6-(4-methylphenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G923-0451
N-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-6-(4-methylphenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G923-0451

Molecular Formula

C27H20ClFN4O (C27 H20 ClFN4 O)

Compound Name

N-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-6-(4-methylphenyl)-2H-pyrazolo[3,4-b]pyridine-4-carboxamide

IUPAC name

N-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-6-(4-methylphenyl)-2H-pyrazolo[34-b]pyridine-4-carboxamide

SMILES

Cc(cc1)ccc1-c1nc2n[nH]c(-c(cc3)ccc3F)c2c(C(NCc(cccc2)c2Cl)=O)c1

InChI

InChI=1S/C27H20ClFN4O/c1-16-6-8-17(9-7-16)23-14-21(27(34)30-15-19-4-2-3-5-22(19)28)24-25(32-33-26(24)31-23)18-10-12-20(29)13-11-18/h2-14H,15H2,1H3,(H,30,34)(H,31,32,33)

InChI Key

YMBABTPMHOHTNS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15075466

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.93

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.273

Distribution Coefficient, logD

7.272

Water Solubility, LogSw

-6.27

Polar Surface Area

57.297

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.40

G923-0451 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G923-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G923-0451?
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What is the minimum amount of G923-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G923-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G923-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G923-0451 available by request