G935-3824 Screening compound: 1-({1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-3,5-dimethyl-1H-pyrazol-4-yl}sulfonyl)-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide

G935-3824 Screening compound: 1-({1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-3,5-dimethyl-1H-pyrazol-4-yl}sulfonyl)-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide
G935-3824 Screening compound: 1-({1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-3,5-dimethyl-1H-pyrazol-4-yl}sulfonyl)-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G935-3824
1-({1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-3,5-dimethyl-1H-pyrazol-4-yl}sulfonyl)-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G935-3824

Molecular Formula

C25H30N6O4S2 (C25 H30 N6 O4 S2)

Compound Name

1-({1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-3,5-dimethyl-1H-pyrazol-4-yl}sulfonyl)-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide

IUPAC name

1-({1-[2-(23-dihydro-1H-indol-1-yl)-2-oxoethyl]-35-dimethyl-1H-pyrazol-4-yl}sulfonyl)-N-(4-methyl-13-thiazol-2-yl)piperidine-3-carboxamide

SMILES

Cc1csc(NC(C(CCC2)CN2S(c2c(C)n(CC(N(CC3)c4c3cccc4)=O)nc2C)(=O)=O)=O)n1

InChI

InChI=1S/C25H30N6O4S2/c1-16-15-36-25(26-16)27-24(33)20-8-6-11-29(13-20)37(34,35)23-17(2)28-31(18(23)3)14-22(32)30-12-10-19-7-4-5-9-21(19)30/h4-5,7,9,15,20H,6,8,10-14H2,1-3H3,(H,26,27,33)/t20-/m0/s1

InChI Key

HZAJCXORKLLWEC-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD15075998

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

542.68

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.583

Distribution Coefficient, logD

1.465

Water Solubility, LogSw

-2.53

Polar Surface Area

94.532

Acid Dissociation Constant (pKa)

7.90

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

G935-3824 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with G935-3824 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G935-3824?
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What is the minimum amount of G935-3824 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G935-3824
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G935-3824
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G935-3824 available by request