G937-0236 Screening compound: ethyl 2,5-dimethyl-4-[(4-{[4-(1,2-oxazol-5-yl)phenyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

G937-0236 Screening compound: ethyl 2,5-dimethyl-4-[(4-{[4-(1,2-oxazol-5-yl)phenyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate
G937-0236 Screening compound: ethyl 2,5-dimethyl-4-[(4-{[4-(1,2-oxazol-5-yl)phenyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-0236
ethyl 2,5-dimethyl-4-[(4-{[4-(1,2-oxazol-5-yl)phenyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-0236

Molecular Formula

C24H28N4O6S (C24 H28 N4 O6 S)

Compound Name

ethyl 2,5-dimethyl-4-[(4-{[4-(1,2-oxazol-5-yl)phenyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 25-dimethyl-4-[(4-{[4-(12-oxazol-5-yl)phenyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)[nH]c(C)c1S(N(CC1)CCC1C(Nc(cc1)ccc1-c1ccno1)=O)(=O)=O)=O

InChI

InChI=1S/C24H28N4O6S/c1-4-33-24(30)21-15(2)26-16(3)22(21)35(31,32)28-13-10-18(11-14-28)23(29)27-19-7-5-17(6-8-19)20-9-12-25-34-20/h5-9,12,18,26H,4,10-11,13-14H2,1-3H3,(H,27,29)

InChI Key

OCNHSHRKOXLVRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27168197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

500.58

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.149

Distribution Coefficient, logD

2.149

Water Solubility, LogSw

-2.71

Polar Surface Area

108.451

Acid Dissociation Constant (pKa)

12.42

Base Dissociation Constant (pKb)

1.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G937-0236 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G937-0236 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-0236?
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What is the minimum amount of G937-0236 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-0236
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-0236
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-0236 available by request