G937-0524 Screening compound: ethyl 1,2,5-trimethyl-4-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

G937-0524 Screening compound: ethyl 1,2,5-trimethyl-4-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate
G937-0524 Screening compound: ethyl 1,2,5-trimethyl-4-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-0524
ethyl 1,2,5-trimethyl-4-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-0524

Molecular Formula

C25H35N5O5S (C25 H35 N5 O5 S)

Compound Name

ethyl 1,2,5-trimethyl-4-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 125-trimethyl-4-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)n(C)c(C)c1S(N(CC1)CCC1C(N(CC1)CCN1c1ncccc1)=O)(=O)=O)=O

InChI

InChI=1S/C25H35N5O5S/c1-5-35-25(32)22-18(2)27(4)19(3)23(22)36(33,34)30-12-9-20(10-13-30)24(31)29-16-14-28(15-17-29)21-8-6-7-11-26-21/h6-8,11,20H,5,9-10,12-17H2,1-4H3

InChI Key

LGHOGYOVOPALNI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27168251

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

517.65

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.854

Distribution Coefficient, logD

1.845

Water Solubility, LogSw

-2.30

Polar Surface Area

83.902

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

G937-0524 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G937-0524 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-0524?
Check Price and Availability of G937-0524, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G937-0524 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-0524
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-0524
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-0524 available by request