G937-1580 Screening compound: ethyl 1,2,5-trimethyl-4-({3-[(4-methyl-1,3-thiazol-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

G937-1580 Screening compound: ethyl 1,2,5-trimethyl-4-({3-[(4-methyl-1,3-thiazol-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate
G937-1580 Screening compound: ethyl 1,2,5-trimethyl-4-({3-[(4-methyl-1,3-thiazol-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-1580
ethyl 1,2,5-trimethyl-4-({3-[(4-methyl-1,3-thiazol-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-1580

Molecular Formula

C20H28N4O5S2 (C20 H28 N4 O5 S2)

Compound Name

ethyl 1,2,5-trimethyl-4-({3-[(4-methyl-1,3-thiazol-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 125-trimethyl-4-({3-[(4-methyl-13-thiazol-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)n(C)c(C)c1S(N(CCC1)CC1C(Nc1nc(C)cs1)=O)(=O)=O)=O

InChI

InChI=1S/C20H28N4O5S2/c1-6-29-19(26)16-13(3)23(5)14(4)17(16)31(27,28)24-9-7-8-15(10-24)18(25)22-20-21-12(2)11-30-20/h11,15H,6-10H2,1-5H3,(H,21,22,25)/t15-/m0/s1

InChI Key

ZTLGSLGSWZSGSZ-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD15076060

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.6

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.603

Distribution Coefficient, logD

1.484

Water Solubility, LogSw

-2.35

Polar Surface Area

88.360

Acid Dissociation Constant (pKa)

7.90

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.00

G937-1580 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G937-1580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-1580?
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What is the minimum amount of G937-1580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-1580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-1580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-1580 available by request