G937-1591 Screening compound: ethyl 1,2,5-trimethyl-4-[(3-{[(pyridin-3-yl)methyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

G937-1591 Screening compound: ethyl 1,2,5-trimethyl-4-[(3-{[(pyridin-3-yl)methyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate
G937-1591 Screening compound: ethyl 1,2,5-trimethyl-4-[(3-{[(pyridin-3-yl)methyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-1591
ethyl 1,2,5-trimethyl-4-[(3-{[(pyridin-3-yl)methyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-1591

Molecular Formula

C22H30N4O5S (C22 H30 N4 O5 S)

Compound Name

ethyl 1,2,5-trimethyl-4-[(3-{[(pyridin-3-yl)methyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 125-trimethyl-4-[(3-{[(pyridin-3-yl)methyl]carbamoyl}piperidin-1-yl)sulfonyl]-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)n(C)c(C)c1S(N(CCC1)CC1C(NCc1cnccc1)=O)(=O)=O)=O

InChI

InChI=1S/C22H30N4O5S/c1-5-31-22(28)19-15(2)25(4)16(3)20(19)32(29,30)26-11-7-9-18(14-26)21(27)24-13-17-8-6-10-23-12-17/h6,8,10,12,18H,5,7,9,11,13-14H2,1-4H3,(H,24,27)/t18-/m0/s1

InChI Key

HVCMDDGJTAEINM-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15076064

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.57

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.326

Distribution Coefficient, logD

0.324

Water Solubility, LogSw

-1.73

Polar Surface Area

89.347

Acid Dissociation Constant (pKa)

12.74

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G937-1591 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Others
  • GPCR
  • Kinases
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G937-1591 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-1591?
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What is the minimum amount of G937-1591 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-1591
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-1591
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-1591 available by request