G937-1732 Screening compound: ethyl 4-({3-[(3-chloro-4-fluorophenyl)carbamoyl]piperidin-1-yl}sulfonyl)-1,2,5-trimethyl-1H-pyrrole-3-carboxylate

G937-1732 Screening compound: ethyl 4-({3-[(3-chloro-4-fluorophenyl)carbamoyl]piperidin-1-yl}sulfonyl)-1,2,5-trimethyl-1H-pyrrole-3-carboxylate
G937-1732 Screening compound: ethyl 4-({3-[(3-chloro-4-fluorophenyl)carbamoyl]piperidin-1-yl}sulfonyl)-1,2,5-trimethyl-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-1732
ethyl 4-({3-[(3-chloro-4-fluorophenyl)carbamoyl]piperidin-1-yl}sulfonyl)-1,2,5-trimethyl-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-1732

Molecular Formula

C22H27ClFN3O5S (C22 H27 ClFN3 O5 S)

Compound Name

ethyl 4-({3-[(3-chloro-4-fluorophenyl)carbamoyl]piperidin-1-yl}sulfonyl)-1,2,5-trimethyl-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 4-({3-[(3-chloro-4-fluorophenyl)carbamoyl]piperidin-1-yl}sulfonyl)-125-trimethyl-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)n(C)c(C)c1S(N(CCC1)CC1C(Nc(cc1)cc(Cl)c1F)=O)(=O)=O)=O

InChI

InChI=1S/C22H27ClFN3O5S/c1-5-32-22(29)19-13(2)26(4)14(3)20(19)33(30,31)27-10-6-7-15(12-27)21(28)25-16-8-9-18(24)17(23)11-16/h8-9,11,15H,5-7,10,12H2,1-4H3,(H,25,28)/t15-/m0/s1

InChI Key

LULLBGNVAHOFLV-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD15076126

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.99

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.595

Distribution Coefficient, logD

2.444

Water Solubility, LogSw

-3.67

Polar Surface Area

78.507

Acid Dissociation Constant (pKa)

7.78

Base Dissociation Constant (pKb)

-0.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.50

G937-1732 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G937-1732 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-1732?
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What is the minimum amount of G937-1732 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-1732
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-1732
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-1732 available by request