G937-1786 Screening compound: ethyl 1,2,5-trimethyl-4-({3-[(pyridin-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

G937-1786 Screening compound: ethyl 1,2,5-trimethyl-4-({3-[(pyridin-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate
G937-1786 Screening compound: ethyl 1,2,5-trimethyl-4-({3-[(pyridin-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-1786
ethyl 1,2,5-trimethyl-4-({3-[(pyridin-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-1786

Molecular Formula

C21H28N4O5S (C21 H28 N4 O5 S)

Compound Name

ethyl 1,2,5-trimethyl-4-({3-[(pyridin-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 125-trimethyl-4-({3-[(pyridin-2-yl)carbamoyl]piperidin-1-yl}sulfonyl)-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)n(C)c(C)c1S(N(CCC1)CC1C(Nc1ncccc1)=O)(=O)=O)=O

InChI

InChI=1S/C21H28N4O5S/c1-5-30-21(27)18-14(2)24(4)15(3)19(18)31(28,29)25-12-8-9-16(13-25)20(26)23-17-10-6-7-11-22-17/h6-7,10-11,16H,5,8-9,12-13H2,1-4H3,(H,22,23,26)/t16-/m0/s1

InChI Key

RSHWEPCFPFPCQK-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15076137

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.54

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.331

Distribution Coefficient, logD

1.328

Water Solubility, LogSw

-2.43

Polar Surface Area

88.122

Acid Dissociation Constant (pKa)

9.55

Base Dissociation Constant (pKb)

3.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.60

G937-1786 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G937-1786 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-1786?
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What is the minimum amount of G937-1786 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-1786
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-1786
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-1786 available by request