G943-0194 Screening compound: 4-cyano-N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)benzamide

G943-0194 Screening compound: 4-cyano-N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)benzamide
G943-0194 Screening compound: 4-cyano-N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-0194
4-cyano-N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-0194

Molecular Formula

C23H17N3O2S (C23 H17 N3 O2 S)

Compound Name

4-cyano-N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)benzamide

IUPAC name

4-cyano-N-{9-ethyl-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(11)3571214-hexaen-5-yl}benzamide

SMILES

CCN(c(ccc(NC(c(cc1)ccc1C#N)=O)c1)c1Sc1c2cccc1)C2=O

InChI

InChI=1S/C23H17N3O2S/c1-2-26-19-12-11-17(25-22(27)16-9-7-15(14-24)8-10-16)13-21(19)29-20-6-4-3-5-18(20)23(26)28/h3-13H,2H2,1H3,(H,25,27)

InChI Key

TZZPTYJNADAZBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27168917

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.622

Distribution Coefficient, logD

4.622

Water Solubility, LogSw

-4.29

Polar Surface Area

55.544

Acid Dissociation Constant (pKa)

11.24

Base Dissociation Constant (pKb)

-2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

G943-0194 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-0194 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-0194?
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What is the minimum amount of G943-0194 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-0194
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-0194
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-0194 available by request