G943-0297 Screening compound: N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)-4-(trifluoromethyl)benzamide

G943-0297 Screening compound: N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)-4-(trifluoromethyl)benzamide
G943-0297 Screening compound: N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)-4-(trifluoromethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-0297
N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)-4-(trifluoromethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-0297

Molecular Formula

C23H17F3N2O2S (C23 H17 F3 N2 O2 S)

Compound Name

N~1~-(10-ethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)-4-(trifluoromethyl)benzamide

IUPAC name

N-{9-ethyl-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(11)3571214-hexaen-5-yl}-4-(trifluoromethyl)benzamide

SMILES

CCN(c(ccc(NC(c1ccc(C(F)(F)F)cc1)=O)c1)c1Sc1c2cccc1)C2=O

InChI

InChI=1S/C23H17F3N2O2S/c1-2-28-18-12-11-16(13-20(18)31-19-6-4-3-5-17(19)22(28)30)27-21(29)14-7-9-15(10-8-14)23(24,25)26/h3-13H,2H2,1H3,(H,27,29)

InChI Key

OYIPLQNYDVBOHB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27168931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.840

Distribution Coefficient, logD

5.840

Water Solubility, LogSw

-5.53

Polar Surface Area

38.488

Acid Dissociation Constant (pKa)

11.75

Base Dissociation Constant (pKb)

-2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G943-0297 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-0297 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-0297?
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What is the minimum amount of G943-0297 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-0297
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-0297
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-0297 available by request