G943-0437 Screening compound: 2-(4-methylphenyl)-N~1~-(11-oxo-10-propyl-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)acetamide

G943-0437 Screening compound: 2-(4-methylphenyl)-N~1~-(11-oxo-10-propyl-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)acetamide
G943-0437 Screening compound: 2-(4-methylphenyl)-N~1~-(11-oxo-10-propyl-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-0437
2-(4-methylphenyl)-N~1~-(11-oxo-10-propyl-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-0437

Molecular Formula

C25H24N2O2S (C25 H24 N2 O2 S)

Compound Name

2-(4-methylphenyl)-N~1~-(11-oxo-10-propyl-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)acetamide

IUPAC name

2-(4-methylphenyl)-N-{10-oxo-9-propyl-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(11)3571214-hexaen-5-yl}acetamide

SMILES

CCCN(c(ccc(NC(Cc1ccc(C)cc1)=O)c1)c1Sc1c2cccc1)C2=O

InChI

InChI=1S/C25H24N2O2S/c1-3-14-27-21-13-12-19(26-24(28)15-18-10-8-17(2)9-11-18)16-23(21)30-22-7-5-4-6-20(22)25(27)29/h4-13,16H,3,14-15H2,1-2H3,(H,26,28)

InChI Key

BVBLJXWQWBTFPC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27168966

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.809

Distribution Coefficient, logD

5.809

Water Solubility, LogSw

-5.47

Polar Surface Area

38.528

Acid Dissociation Constant (pKa)

12.73

Base Dissociation Constant (pKb)

-1.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G943-0437 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-0437?
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What is the minimum amount of G943-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-0437 available by request