G943-0615 Screening compound: 2-(4-chlorophenyl)-N~1~-{2-[(10-cyclopentyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)amino]-2-oxoethyl}acetamide

G943-0615 Screening compound: 2-(4-chlorophenyl)-N~1~-{2-[(10-cyclopentyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)amino]-2-oxoethyl}acetamide
G943-0615 Screening compound: 2-(4-chlorophenyl)-N~1~-{2-[(10-cyclopentyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)amino]-2-oxoethyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-0615
2-(4-chlorophenyl)-N~1~-{2-[(10-cyclopentyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)amino]-2-oxoethyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-0615

Molecular Formula

C28H26ClN3O3S (C28 H26 ClN3 O3 S)

Compound Name

2-(4-chlorophenyl)-N~1~-{2-[(10-cyclopentyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl)amino]-2-oxoethyl}acetamide

IUPAC name

2-(4-chlorophenyl)-N-[({9-cyclopentyl-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(11)3571214-hexaen-5-yl}carbamoyl)methyl]acetamide

SMILES

O=C(Cc(cc1)ccc1Cl)NCC(Nc(cc1)cc(Sc2c3cccc2)c1N(C1CCCC1)C3=O)=O

InChI

InChI=1S/C28H26ClN3O3S/c29-19-11-9-18(10-12-19)15-26(33)30-17-27(34)31-20-13-14-23-25(16-20)36-24-8-4-3-7-22(24)28(35)32(23)21-5-1-2-6-21/h3-4,7-14,16,21H,1-2,5-6,15,17H2,(H,30,33)(H,31,34)

InChI Key

SFBYHJONCAHALV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27169026

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

520.05

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.658

Distribution Coefficient, logD

5.658

Water Solubility, LogSw

-6.00

Polar Surface Area

62.337

Acid Dissociation Constant (pKa)

12.78

Base Dissociation Constant (pKb)

-0.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G943-0615 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-0615 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-0615?
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What is the minimum amount of G943-0615 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-0615
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-0615
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-0615 available by request