G943-1143 Screening compound: 3-chloro-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

G943-1143 Screening compound: 3-chloro-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide
G943-1143 Screening compound: 3-chloro-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-1143
3-chloro-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-1143

Molecular Formula

C23H19ClN2O3S (C23 H19 ClN2 O3 S)

Compound Name

3-chloro-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

IUPAC name

3-chloro-N-[9-(2-methoxyethyl)-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(15)3(8)461113-hexaen-5-yl]benzamide

SMILES

COCCN(c(ccc(NC(c1cccc(Cl)c1)=O)c1)c1Sc1c2cccc1)C2=O

InChI

InChI=1S/C23H19ClN2O3S/c1-29-12-11-26-19-10-9-17(25-22(27)15-5-4-6-16(24)13-15)14-21(19)30-20-8-3-2-7-18(20)23(26)28/h2-10,13-14H,11-12H2,1H3,(H,25,27)

InChI Key

MTMPBPCKCFSLGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27169089

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.191

Distribution Coefficient, logD

5.191

Water Solubility, LogSw

-5.33

Polar Surface Area

47.084

Acid Dissociation Constant (pKa)

10.95

Base Dissociation Constant (pKb)

-3.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G943-1143 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-1143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-1143?
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What is the minimum amount of G943-1143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-1143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-1143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-1143 available by request