G943-1152 Screening compound: 3,5-dimethoxy-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

G943-1152 Screening compound: 3,5-dimethoxy-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide
G943-1152 Screening compound: 3,5-dimethoxy-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-1152
3,5-dimethoxy-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-1152

Molecular Formula

C25H24N2O5S (C25 H24 N2 O5 S)

Compound Name

3,5-dimethoxy-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

IUPAC name

35-dimethoxy-N-[9-(2-methoxyethyl)-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(15)3(8)461113-hexaen-5-yl]benzamide

SMILES

COCCN(c(ccc(NC(c1cc(OC)cc(OC)c1)=O)c1)c1Sc1c2cccc1)C2=O

InChI

InChI=1S/C25H24N2O5S/c1-30-11-10-27-21-9-8-17(14-23(21)33-22-7-5-4-6-20(22)25(27)29)26-24(28)16-12-18(31-2)15-19(13-16)32-3/h4-9,12-15H,10-11H2,1-3H3,(H,26,28)

InChI Key

XBNFSUVCLJFDQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27644262

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.794

Distribution Coefficient, logD

4.794

Water Solubility, LogSw

-4.42

Polar Surface Area

62.172

Acid Dissociation Constant (pKa)

13.06

Base Dissociation Constant (pKb)

-3.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G943-1152 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-1152 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-1152?
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What is the minimum amount of G943-1152 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-1152
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-1152
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-1152 available by request