G943-1172 Screening compound: N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]-4-methylbenzamide

G943-1172 Screening compound: N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]-4-methylbenzamide
G943-1172 Screening compound: N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-1172
N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-1172

Molecular Formula

C24H22N2O3S (C24 H22 N2 O3 S)

Compound Name

N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]-4-methylbenzamide

IUPAC name

N-[9-(2-methoxyethyl)-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(15)3(8)461113-hexaen-5-yl]-4-methylbenzamide

SMILES

Cc(cc1)ccc1C(Nc(cc1)cc(Sc2c3cccc2)c1N(CCOC)C3=O)=O

InChI

InChI=1S/C24H22N2O3S/c1-16-7-9-17(10-8-16)23(27)25-18-11-12-20-22(15-18)30-21-6-4-3-5-19(21)24(28)26(20)13-14-29-2/h3-12,15H,13-14H2,1-2H3,(H,25,27)

InChI Key

RBYZGFHNLMFOKN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27169098

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.952

Distribution Coefficient, logD

4.952

Water Solubility, LogSw

-4.47

Polar Surface Area

47.084

Acid Dissociation Constant (pKa)

11.75

Base Dissociation Constant (pKb)

-3.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

G943-1172 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-1172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-1172?
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What is the minimum amount of G943-1172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-1172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-1172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-1172 available by request