G943-1229 Screening compound: 4-(acetylamino)-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

G943-1229 Screening compound: 4-(acetylamino)-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide
G943-1229 Screening compound: 4-(acetylamino)-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G943-1229
4-(acetylamino)-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G943-1229

Molecular Formula

C25H23N3O4S (C25 H23 N3 O4 S)

Compound Name

4-(acetylamino)-N~1~-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]benzamide

IUPAC name

4-acetamido-N-[9-(2-methoxyethyl)-10-oxo-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(15)3(8)461113-hexaen-5-yl]benzamide

SMILES

CC(Nc(cc1)ccc1C(Nc(cc1)cc(Sc2c3cccc2)c1N(CCOC)C3=O)=O)=O

InChI

InChI=1S/C25H23N3O4S/c1-16(29)26-18-9-7-17(8-10-18)24(30)27-19-11-12-21-23(15-19)33-22-6-4-3-5-20(22)25(31)28(21)13-14-32-2/h3-12,15H,13-14H2,1-2H3,(H,26,29)(H,27,30)

InChI Key

LAXWYZHLUQXBNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27169116

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.730

Distribution Coefficient, logD

3.729

Water Solubility, LogSw

-3.96

Polar Surface Area

70.346

Acid Dissociation Constant (pKa)

10.78

Base Dissociation Constant (pKb)

-0.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

G943-1229 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G943-1229 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G943-1229?
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What is the minimum amount of G943-1229 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G943-1229
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G943-1229
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G943-1229 available by request