G948-5127 Screening compound: 1-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylbenzenesulfonyl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

G948-5127 Screening compound: 1-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylbenzenesulfonyl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide
G948-5127 Screening compound: 1-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylbenzenesulfonyl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G948-5127
1-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylbenzenesulfonyl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G948-5127

Molecular Formula

C24H27N5O4S (C24 H27 N5 O4 S)

Compound Name

1-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylbenzenesulfonyl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-[5-(5-cyclopropyl-124-oxadiazol-3-yl)-2-methylbenzenesulfonyl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

SMILES

Cc(ccc(-c1noc(C2CC2)n1)c1)c1S(N(CC1)CCC1C(NCc1ncccc1)=O)(=O)=O

InChI

InChI=1S/C24H27N5O4S/c1-16-5-6-19(22-27-24(33-28-22)18-7-8-18)14-21(16)34(31,32)29-12-9-17(10-13-29)23(30)26-15-20-4-2-3-11-25-20/h2-6,11,14,17-18H,7-10,12-13,15H2,1H3,(H,26,30)

InChI Key

TYCJIMBCXIODRL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27644017

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.488

Distribution Coefficient, logD

3.488

Water Solubility, LogSw

-3.67

Polar Surface Area

97.835

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

G948-5127 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Immune system
  • animal
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with G948-5127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G948-5127?
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What is the minimum amount of G948-5127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G948-5127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G948-5127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G948-5127 available by request