G949-2053 Screening compound: 1-[2-chloro-5-(5-methyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-(2-methylphenyl)piperidine-3-carboxamide

G949-2053 Screening compound: 1-[2-chloro-5-(5-methyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-(2-methylphenyl)piperidine-3-carboxamide
G949-2053 Screening compound: 1-[2-chloro-5-(5-methyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-(2-methylphenyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G949-2053
1-[2-chloro-5-(5-methyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-(2-methylphenyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G949-2053

Molecular Formula

C22H23ClN4O4S (C22 H23 ClN4 O4 S)

Compound Name

1-[2-chloro-5-(5-methyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-(2-methylphenyl)piperidine-3-carboxamide

IUPAC name

1-[2-chloro-5-(5-methyl-124-oxadiazol-3-yl)benzenesulfonyl]-N-(2-methylphenyl)piperidine-3-carboxamide

SMILES

Cc1nc(-c(cc2)cc(S(N(CCC3)CC3C(Nc3c(C)cccc3)=O)(=O)=O)c2Cl)no1

InChI

InChI=1S/C22H23ClN4O4S/c1-14-6-3-4-8-19(14)25-22(28)17-7-5-11-27(13-17)32(29,30)20-12-16(9-10-18(20)23)21-24-15(2)31-26-21/h3-4,6,8-10,12,17H,5,7,11,13H2,1-2H3,(H,25,28)/t17-/m0/s1

InChI Key

LLENBUYGCPVRSW-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD15077183

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.97

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.541

Distribution Coefficient, logD

3.541

Water Solubility, LogSw

-3.95

Polar Surface Area

85.181

Acid Dissociation Constant (pKa)

11.22

Base Dissociation Constant (pKb)

-0.34

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

G949-2053 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G949-2053 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G949-2053?
Check Price and Availability of G949-2053, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G949-2053 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G949-2053
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G949-2053
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G949-2053 available by request