G953-0018 Screening compound: 2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,4-dimethylphenyl)acetamide

G953-0018 Screening compound: 2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,4-dimethylphenyl)acetamide
G953-0018 Screening compound: 2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,4-dimethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G953-0018
2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,4-dimethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G953-0018

Molecular Formula

C22H27N5O2 (C22 H27 N5 O2)

Compound Name

2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,4-dimethylphenyl)acetamide

IUPAC name

2-[2-(35-dimethyl-1H-pyrazol-1-yl)-5-ethyl-4-methyl-6-oxo-16-dihydropyrimidin-1-yl]-N-(24-dimethylphenyl)acetamide

SMILES

CCC1=C(C)N=C(n2nc(C)cc2C)N(CC(Nc2c(C)cc(C)cc2)=O)C1=O

InChI

InChI=1S/C22H27N5O2/c1-7-18-17(6)23-22(27-16(5)11-15(4)25-27)26(21(18)29)12-20(28)24-19-9-8-13(2)10-14(19)3/h8-11H,7,12H2,1-6H3,(H,24,28)

InChI Key

MSHCKGNFEOBQLR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239673

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.434

Distribution Coefficient, logD

2.434

Water Solubility, LogSw

-2.73

Polar Surface Area

61.345

Acid Dissociation Constant (pKa)

12.62

Base Dissociation Constant (pKb)

1.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G953-0018 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G953-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G953-0018?
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What is the minimum amount of G953-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G953-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G953-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G953-0018 available by request