G953-0139 Screening compound: N-(2,4-difluorophenyl)-2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-ethyl-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide

G953-0139 Screening compound: N-(2,4-difluorophenyl)-2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-ethyl-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide
G953-0139 Screening compound: N-(2,4-difluorophenyl)-2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-ethyl-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G953-0139
N-(2,4-difluorophenyl)-2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-ethyl-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G953-0139

Molecular Formula

C19H19F2N5O2 (C19 H19 F2 N5 O2)

Compound Name

N-(2,4-difluorophenyl)-2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-ethyl-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(24-difluorophenyl)-2-[2-(35-dimethyl-1H-pyrazol-1-yl)-4-ethyl-6-oxo-16-dihydropyrimidin-1-yl]acetamide

SMILES

CCC(N=C(n1nc(C)cc1C)N1CC(Nc(ccc(F)c2)c2F)=O)=CC1=O

InChI

InChI=1S/C19H19F2N5O2/c1-4-14-9-18(28)25(19(22-14)26-12(3)7-11(2)24-26)10-17(27)23-16-6-5-13(20)8-15(16)21/h5-9H,4,10H2,1-3H3,(H,23,27)

InChI Key

OZHJGWXWBGVTIG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08534643

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.821

Distribution Coefficient, logD

1.815

Water Solubility, LogSw

-2.43

Polar Surface Area

62.434

Acid Dissociation Constant (pKa)

9.29

Base Dissociation Constant (pKb)

-0.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

G953-0139 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G953-0139 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G953-0139?
Check Price and Availability of G953-0139, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G953-0139 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G953-0139
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G953-0139
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G953-0139 available by request