G953-0280 Screening compound: 3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one

G953-0280 Screening compound: 3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one
G953-0280 Screening compound: 3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G953-0280
3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G953-0280

Molecular Formula

C23H25N5O2 (C23 H25 N5 O2)

Compound Name

3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one

IUPAC name

3-[2-(23-dihydro-1H-indol-1-yl)-2-oxoethyl]-2-(35-dimethyl-1H-pyrazol-1-yl)-345678-hexahydroquinazolin-4-one

SMILES

Cc1cc(C)nn1C(N1CC(N(CC2)c3c2cccc3)=O)=NC(CCCC2)=C2C1=O

InChI

InChI=1S/C23H25N5O2/c1-15-13-16(2)28(25-15)23-24-19-9-5-4-8-18(19)22(30)27(23)14-21(29)26-12-11-17-7-3-6-10-20(17)26/h3,6-7,10,13H,4-5,8-9,11-12,14H2,1-2H3

InChI Key

SFAUPBGOIMIQGT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08958799

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.737

Distribution Coefficient, logD

1.737

Water Solubility, LogSw

-2.15

Polar Surface Area

54.636

Acid Dissociation Constant (pKa)

24.29

Base Dissociation Constant (pKb)

2.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G953-0280 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G953-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G953-0280?
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What is the minimum amount of G953-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G953-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G953-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G953-0280 available by request