H024-0127 Screening compound: N-[(pyridin-2-yl)methyl]-2-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]acetamide

H024-0127 Screening compound: N-[(pyridin-2-yl)methyl]-2-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]acetamide
H024-0127 Screening compound: N-[(pyridin-2-yl)methyl]-2-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound H024-0127
N-[(pyridin-2-yl)methyl]-2-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H024-0127

Molecular Formula

C15H14N6O (C15 H14 N6 O)

Compound Name

N-[(pyridin-2-yl)methyl]-2-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]acetamide

IUPAC name

N-[(pyridin-2-yl)methyl]-2-[5-(pyridin-4-yl)-4H-124-triazol-3-yl]acetamide

SMILES

O=C(Cc1nnc(-c2ccncc2)[nH]1)NCc1ncccc1

InChI

InChI=1S/C15H14N6O/c22-14(18-10-12-3-1-2-6-17-12)9-13-19-15(21-20-13)11-4-7-16-8-5-11/h1-8H,9-10H2,(H,18,22)(H,19,20,21)

InChI Key

XVAWHWWZUFAAAT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27214373

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

294.32

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.082

Distribution Coefficient, logD

0.049

Water Solubility, LogSw

-0.92

Polar Surface Area

78.185

Acid Dissociation Constant (pKa)

8.51

Base Dissociation Constant (pKb)

4.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

H024-0127 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with H024-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H024-0127?
Check Price and Availability of H024-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of H024-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H024-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H024-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H024-0127 available by request