H024-0191 Screening compound: 4-{[1,1'-biphenyl]-4-yl}-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine

H024-0191 Screening compound: 4-{[1,1'-biphenyl]-4-yl}-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine
H024-0191 Screening compound: 4-{[1,1'-biphenyl]-4-yl}-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound H024-0191
4-{[1,1'-biphenyl]-4-yl}-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H024-0191

Molecular Formula

C22H14ClF3N2S (C22 H14 ClF3 N2 S)

Compound Name

4-{[1,1'-biphenyl]-4-yl}-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine

IUPAC name

4-{[11'-biphenyl]-4-yl}-N-[4-chloro-3-(trifluoromethyl)phenyl]-13-thiazol-2-amine

SMILES

FC(c(cc(cc1)Nc2nc(-c(cc3)ccc3-c3ccccc3)cs2)c1Cl)(F)F

InChI

InChI=1S/C22H14ClF3N2S/c23-19-11-10-17(12-18(19)22(24,25)26)27-21-28-20(13-29-21)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-13H,(H,27,28)

InChI Key

SLXGMSYYEXTWGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27214414

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.88

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

8.612

Distribution Coefficient, logD

8.612

Water Solubility, LogSw

-7.19

Polar Surface Area

18.654

Acid Dissociation Constant (pKa)

16.46

Base Dissociation Constant (pKb)

2.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

H024-0191 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with H024-0191 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H024-0191?
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What is the minimum amount of H024-0191 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H024-0191
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H024-0191
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H024-0191 available by request