H025-3074C Screening compound: N-{6-[(dimethylamino)methyl]-3-[(3-fluorophenyl)sulfonyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}-N-methylamine

H025-3074C Screening compound: N-{6-[(dimethylamino)methyl]-3-[(3-fluorophenyl)sulfonyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}-N-methylamine
H025-3074C Screening compound: N-{6-[(dimethylamino)methyl]-3-[(3-fluorophenyl)sulfonyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}-N-methylamine alternative view

Chemical Structure Depiction of ChemDiv screening compound H025-3074C
N-{6-[(dimethylamino)methyl]-3-[(3-fluorophenyl)sulfonyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}-N-methylamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H025-3074C

Molecular Formula

C18H22FN5O2S (C18 H22 FN5 O2 S)

Compound Name

N-{6-[(dimethylamino)methyl]-3-[(3-fluorophenyl)sulfonyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}-N-methylamine

IUPAC name

6-[(dimethylamino)methyl]-3-(3-fluorobenzenesulfonyl)-N57-trimethylpyrazolo[15-a]pyrimidin-2-amine

SMILES

Cc(n1nc2NC)c(CN(C)C)c(C)nc1c2S(c1cc(F)ccc1)(=O)=O

InChI

InChI=1S/C18H22FN5O2S/c1-11-15(10-23(4)5)12(2)24-18(21-11)16(17(20-3)22-24)27(25,26)14-8-6-7-13(19)9-14/h6-9H,10H2,1-5H3,(H,20,22)

InChI Key

KTJQMQPONLEYSK-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

391.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.451

Distribution Coefficient, logD

0.391

Water Solubility, LogSw

-2.49

Polar Surface Area

65.223

Acid Dissociation Constant (pKa)

18.94

Base Dissociation Constant (pKb)

8.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

H025-3074C in Drug Discovery

Included in Screening Libraries

CNS Annotated Library (688 compounds)

CNS Targets (44014 compounds)

Human GPCR Annotated Library (5539 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with H025-3074C chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H025-3074C?
Check Price and Availability of H025-3074C, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of H025-3074C you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H025-3074C
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H025-3074C
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H025-3074C available by request