H027-4239 Screening compound: 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2(1H)-pyrimidinone

H027-4239 Screening compound: 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2(1H)-pyrimidinone
H027-4239 Screening compound: 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2(1H)-pyrimidinone alternative view

Chemical Structure Depiction of ChemDiv screening compound H027-4239
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2(1H)-pyrimidinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H027-4239

Molecular Formula

C9H11F2N3O4 (C9 H11 F2 N3 O4)

Compound Name

4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2(1H)-pyrimidinone

IUPAC name

4-amino-1-[(2R4R5R)-33-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-12-dihydropyrimidin-2-one

SMILES

NC(C=CN1[C@@H](C2(F)F)O[C@H](CO)[C@H]2O)=NC1=O

InChI

InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6+,7+/m0/s1

InChI Key

SDUQYLNIPVEERB-UBKIQSJTSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

263.2

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

-1.500

Distribution Coefficient, logD

-1.500

Water Solubility, LogSw

-0.19

Polar Surface Area

86.473

Acid Dissociation Constant (pKa)

13.56

Base Dissociation Constant (pKb)

2.77

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

55.56

H027-4239 in Drug Discovery

Included in Screening Libraries

Human Kinases Annotated Library (2415 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with H027-4239 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H027-4239?
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What is the minimum amount of H027-4239 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H027-4239
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H027-4239
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H027-4239 available by request