J010-0127 Screening compound: N-[5-(1,3-benzoxazol-2-yl)pyridin-3-yl]-2-(4-methylphenoxy)acetamide

J010-0127 Screening compound: N-[5-(1,3-benzoxazol-2-yl)pyridin-3-yl]-2-(4-methylphenoxy)acetamide
J010-0127 Screening compound: N-[5-(1,3-benzoxazol-2-yl)pyridin-3-yl]-2-(4-methylphenoxy)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J010-0127
N-[5-(1,3-benzoxazol-2-yl)pyridin-3-yl]-2-(4-methylphenoxy)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J010-0127

Molecular Formula

C21H17N3O3 (C21 H17 N3 O3)

Compound Name

N-[5-(1,3-benzoxazol-2-yl)pyridin-3-yl]-2-(4-methylphenoxy)acetamide

IUPAC name

N-[5-(13-benzoxazol-2-yl)pyridin-3-yl]-2-(4-methylphenoxy)acetamide

SMILES

Cc(cc1)ccc1OCC(Nc1cncc(-c2nc(cccc3)c3o2)c1)=O

InChI

InChI=1S/C21H17N3O3/c1-14-6-8-17(9-7-14)26-13-20(25)23-16-10-15(11-22-12-16)21-24-18-4-2-3-5-19(18)27-21/h2-12H,13H2,1H3,(H,23,25)

InChI Key

BLDLSMNEUNVZRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11852562

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.417

Distribution Coefficient, logD

4.417

Water Solubility, LogSw

-4.17

Polar Surface Area

57.033

Acid Dissociation Constant (pKa)

12.91

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

J010-0127 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with J010-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J010-0127?
Check Price and Availability of J010-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J010-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J010-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J010-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J010-0127 available by request