J012-2712 Screening compound: 1-(4-fluorophenyl)-4-(3-hydroxyphenyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

J012-2712 Screening compound: 1-(4-fluorophenyl)-4-(3-hydroxyphenyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one
J012-2712 Screening compound: 1-(4-fluorophenyl)-4-(3-hydroxyphenyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound J012-2712
1-(4-fluorophenyl)-4-(3-hydroxyphenyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J012-2712

Molecular Formula

C18H14FN3O2 (C18 H14 FN3 O2)

Compound Name

1-(4-fluorophenyl)-4-(3-hydroxyphenyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

IUPAC name

1-(4-fluorophenyl)-4-(3-hydroxyphenyl)-1H4H5H6H7H-pyrazolo[34-b]pyridin-6-one

SMILES

Oc1cccc(C(CC(N2)=O)c3c2n(-c(cc2)ccc2F)nc3)c1

InChI

InChI=1S/C18H14FN3O2/c19-12-4-6-13(7-5-12)22-18-16(10-20-22)15(9-17(24)21-18)11-2-1-3-14(23)8-11/h1-8,10,15,23H,9H2,(H,21,24)/t15-/m0/s1

InChI Key

KWDVNFQKJZLVIG-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27216839

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

323.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.899

Distribution Coefficient, logD

2.896

Water Solubility, LogSw

-2.83

Polar Surface Area

56.355

Acid Dissociation Constant (pKa)

9.54

Base Dissociation Constant (pKb)

-2.39

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.10

J012-2712 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with J012-2712 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J012-2712?
Check Price and Availability of J012-2712, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J012-2712 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J012-2712
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J012-2712
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J012-2712 available by request